Growth hormone (GH) is a key hormone involved in growth and metabolism. It is produced by the pituitary gland in the brain. Low growth hormone, also known as growth hormone deficiency, occurs when the pituitary gland does not produce enough growth hormone. This can happen for a variety of reasons:
Some common signs and symptoms of low GH include:
Diagnosing low GH usually involves blood tests to measure IGF-1 levels. IGF-1 is produced by the liver in response to GH. Low IGF-1 indicates inadequate GH production. Stimulation tests are also done to check the pituitary's GH output. Imaging like MRI scans help rule out pituitary tumors.
Treatment for low GH involves replacing the deficient hormone. Synthetic human growth hormone injections (e.g., Norditropin, Humatrope) effectively treat GH deficiency. Pediatric endocrinologists determine the dosage based on the child’s needs. Treatment must be monitored to avoid adverse effects. Lifelong GH therapy may be required for persistent deficiency.
In adults, short-term GH treatment may help reduce fat, increase lean muscle mass, strengthen bones, and improve cholesterol levels. However, long-term safety data is limited. Treatment is generally approved for acquired GH deficiency from pituitary tumors or damage. Talk to your doctor about the pros and cons.
If you or your child show symptoms of low GH, see an endocrinologist for proper evaluation and treatment. Early diagnosis and GH replacement can help optimize growth, body composition, bone health, and quality of life. The specialists at Human Antiaging Center have extensive experience managing growth disorders. Schedule a consultation today to discuss your growth concerns. Our individualized care plans help children and adults reach their full potential.